Hepatic Physiology

<aside> 💡 Know components of a LFT and the underlying physiology for a normal result

Be aware of the limitations of a LFT and demonstrate judicious use of investigations

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• what are the different types of cells in the liver?
• what major blood vessels supply/drain the liver?
• what are the 4 functions of the liver?
• how should you approach LFT interpretation?
• LFT Interpretation Differentials

Hepatocellular Damage & Cholestatic Disease

<aside> 💡 Describe the common causes and clinical presentations of hepatocellular and cholestasis

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• what $\uparrow$ liver enzymes indicate hepatocellular damage (hepatitis) vs cholestasis?
• what does it mean if only a single liver enzyme is elevated?
• what clinical features accompany cholestasis?
• what LFT change is suggestive of alcoholic hepatitis?

Acute & Chronic Liver Disease

<aside> 💡 Describe the common clinical features of acute and chronic liver disease

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• what $\uparrow$ liver enzymes indicate acute injury vs chronic liver disease?
• what are the symptoms of acute injury vs chronic liver disease?
• how does portal HTN develop?
• what are the complications of portal HTN?
• Practice Questions💥