Cholesterol Metabolism
- is cholesterol good or bad?
- what determines lipoprotein **function?
- what are the normal steps of exogenous TG movement?
- what are the normal steps of endogenous TG movement?
- what conditions can disrupt normal TG movement in/out of plasma?
- how is LDL-R expression regulated?
- what 3 types of lipid abnormalities promote atherogenesis?
- what factors favor LDL uptake via macrophage scavenger receptors?
- what are the steps of reverse cholesterol transport?
Familial Hypercholesterolemia
- what is the genetic defect of FH?
- what are the clinical features of FH?
- what are the complications?
Cardiovascular Risk Assessment
- who should be screened for CVD risk?
- who is considered ‘high risk’ for CVD risk?