Learning Objectives

• Outline the pathophysiology of epilepsy, and describe the seizure types associated with different forms of epilepsy (NEURO review)
• Identify the various potential neuronal cellular drug targets for antiepileptic therapy
• Name the major antiepileptic drugs used in Australia and describe their indications, mechanisms of action, common adverse effects and interactions
• Outline the symptoms, prevalence and pathophysiology of Parkinson’s disease and Alzheimer’s disease
• Explain the mechanisms of action of the different classes of drugs used in the treatment of PD and AD, including the role of adjuvant drugs in PD
• Outline the proposed pathophysiology of migraine and relate to the symptoms of this disorder
• Describe the mechanism of action of triptans and CGRP antagonists in the treatment of migraine

Epilepsy

• what is a seizure? - NEURO week 12
• what is epilepsy? - NEURO week 12
• what are generalised seizures?
• what are focal seizures?

Antiepileptics

• what are the 4 main MoA of antiepileptics?
• name are the 5 main antiepileptics used?
• management of epilepsy in pregnancy?
• can medicinal cannabis be used?

Alzheimer’s Disease