Learning Objectives

• Describe the types of immune deficiencies and how they are classified
• Understand the basic mechanisms of immune deficiencies and give examples of different diseases
• Identify some of the signs of immune deficiencies

Immunodeficiencies

• what 4 ‘flags’ suggest an underlying immunodeficiency?
• how are immunodeficiencies classified?
• Infection → Immunodeficiency

Primary Immunodeficiency

• when do PIDs typically present?
• most PIDs are due to [dominant/recessive] traits?
• most PIDs are […] deficiencies?
• Ab deficiencies can be due to [2 things]?
• what are the 3 major categories of B cell defects?
• what quantitative tests can diagnose PID?
• what qualitative tests can diagnose PID?
• what complement deficiencies can exist?
• what 4 defects can occur in phagocytes?
• what are the 3 principal ways that PIDs are treated?