Learning Objectives

• Explain what is meant by risk in terms of genetic analysis
• Evaluate sources and reliability of genetic information
• Explain new genetic tools and applications that affect medicine and how Australia legislates for new genetic technologies
• Describe the main ethical issues associated with the use of novel genetic technologies
• Consider what novel technologies should be considered when dealing with patients

Gene Therapy

• [diseases] have an excellent potential to be treated this way? why?
• what is somatic vs germline gene therapy?
• what 2 methods are used to introduce genes into somatic cells?
• what 3 approaches are used to get genes to the right sites?
• what was the first approved gene therapy?
• what type of gene therapy can be used for multifactorial traits?
• what type of gene therapy can be used for dominant traits?
• how does chromosomal therapy work?
• how does tissue engineering work? advantage?
• what 2 methods are used to produce 3-person babies?
• what is CRISPR-Cas9? how does it work
• Disease → Therapy