Learning Objectives

• Describe the nerve supply to urinary bladder
• Discuss the micturition reflex
• What are the effects of denervation to urinary bladder?
• Define the term ‘renal clearance’ and explain how to measure GFR using renal clearance test
• Explain how renal plasma flow and renal blood flow is measured
• Describe how the effective circulating volume influence renal Na+ excretion
• What are the major signals acting on the kidneys to alter their excretion of Na+
• How do changes in extracellular fluid volume alter Na+ transport in the different segments of the nephron

Micturition

• what is micturition?
• what are 2 important steps in micturition?
• what is the micturition reflex?
• the sensation of a ‘full’ bladder starts at [volume]?
• the urge to void starts at [volume]?
• what does a cystometrogram show?
• Innervation & Effector Function

Micturition Reflex

• what are the components of the micturition reflex?