Learning Objectives
- Define and describe common terms used in pharmacology
- Locate and begin to interpret high quality drug information
- Describe the different systems used to name and classify drugs and give examples of each
- Outline the stages of drug discovery and development
- Describe the main groups of molecular targets for drugs, including the 4 types of receptors
- Explain the different ways by which drugs can act on these targets, giving examples
- Define and contrast agonists and antagonists
- Describe the terms affinity and efficacy, and explain how they relate to drug action at receptors
- Compare the different types of receptor agonists and antagonists
- Describe the relationship between drug concentration and effect
- Measure EC50s and interpret the relationship to potency
- Explain and illustrate the difference between full and partial agonists
- Describe the concepts of constitutive activity and inverse agonism
Drugs
- Terminology
- what 3 names do all drugs have?
- what are the 3 main groups of molecular targets?
- how are adrenergic receptors named?