07 Lipid Digestion & Absorption & Liver Function

Know the dietary sources, dietary requirements and the primary uses in the body of lipids
Know dietary sources of essential fatty acids and trans fatty acids and any health advantages or disadvantages of their consumption
List the enzymes that participate in the digestion of lipids in the GI tract
Describe where, in the GI system, these digestive enzymes are produced and where in the GI tract their digestive action on lipids might be observed
List the absorbable nutrients resulting from the digestion of lipids
Describe where, in the GI tract, and how these nutrients might be absorbed via the enterocytes into the lacteal and blood capillaries
Describe the mechanisms of bile formation, transport and storage, as it is related to the digestion and absorption of lipids in the GI tract
Define the term ‘entero-hepatic circulation’
Describe the processes involved in the metabolism and transport of bilirubin by the liver
Discuss the relationship between alterations in bilirubin metabolism and transport and jaundice
Discuss the important role of the liver in metabolism
Outline the aetiology and pathophysiology of liver disorders including acute and chronic hepatitis, hemochromatosis, Wilson’s Disease, alcoholic liver disease, non-alcoholic steatohepatitis and cirrhosis
Outline some of the liver function tests used in clinical practice