Learning Objectives

• Describe the overall functional processes required for digestive system function
• Outline the electrophysiological properties of GI smooth muscle
• Describe the role of the enteric nervous system and autonomic nervous system involved in regulation of GIT function
• Describe the mechanisms and phases of swallowing
• Describe the response to filling, and the main motility patterns that occur in the stomach
• Explain the types of intestinal motility
• Describe the defecation reflex
• Outline the pathophysiology of gastrointestinal motility disorders

GIT Innervation

• how does the GIT receive parasympathetic innervation?
• what neurotransmitters does the PNS use? what receptors do these act on?
• what are the effects of PNS excitation?
• [nerve roots] provide sympathetic innervation of the GIT?
• how does the GIT receive sympathetic innervation?
• what neurotransmitters does the SNS use? what receptors do these act on?
• what are the effects of SNS excitation?
• what is the enteric nervous system (ENS)?
• what neurotransmitters does the ENS use?