Learning Objectives
- Define inflammation and explain its role in health and disease
- Outline the mechanisms responsible for the 5 cardinal signs of inflammation
- Identify the main stimuli which trigger an acute inflammatory response
- Name the cells and mechanisms responsible for recognising microbes and damaged cells
- Describe the vascular changes involved in acute inflammation and the mechanisms responsible
- Describe the cellular events involved in recruitment of leukocytes to the site of inflammation
- Outline the processes involved in leukocyte activation and cell destruction
- Describe and identify the different morphological patterns of acute inflammation
- List the cell-derived and plasma protein-derived mediators of inflammation, identify their sources and describe their major actions
Inflammation
- what is inflammation?
- why is inflammation bad then?
- what are the 5 cardinal signs of inflammation?
Acute Inflammatory Response
- what stimuli can trigger an acute inflammatory response?
- how are these stimuli recognised?
- what vascular changes occur during acute inflammation?
- what cellular changes occur during acute inflammation?