Learning Objectives

• Demonstrate an understanding of how genes and genomes dictate how an organism functions and develops
• Explain why the human genome project is changing not only science, but medicine as well
• Outline how genetic testing can have ethical and moral issues
• Demonstrate an understanding of how a change at the gene level can result in disease
• Demonstrate an understanding of chromosome structure and nomenclature
• Understand and describe what a karyotype is

Genome Basics

• what is a gene?
• what is a genome? size in humans?
• what is microRNA? function?
• what % of the human genome codes for proteins (exome)?
• what % of the genome has a known biochemical function?
• what is a transcriptome vs a proteome vs an exome?
• how do transcriptomes relate to cell function?
• which nucleotides are prominent in gene-dense vs gene-poor sections?
• what does each section stain (dark or light)?
• what makes the genome ‘messy?’
• what are highly conserved genes?